Beckmann rearrangement of N-(α-hydroxyiminoalkylphosphonyl)amino acids. A convenient synthetic approach to novel peptide-transition-state analogs

Article abstract of DOI:10.1016/0040-4039(92)88143-S

Thermal Beckmann rearrangement of N-(α-hydroxyiminoalkylphosphonyl)amino acid derivatives (2) yields acylphosphordiamidates ( 3 ), which represent a new type of peptide analogs.