Synthesis, structure and reactivity of imidazo[1,2-a] [1,8]naphthyridines

Article abstract of DOI:10.1002/jhet.5570340311

The synthesis and reactivity of imidazo[1,2-a][1,8]naphthyridines are reported. Electrophilic substitution reactions were studied and the site of the reaction was established with the aid of high-field ¹H and ¹³C nmr spectra. The experimental C-1 position reaction was correlated with a CNDO/2 calculations.