Tandem enzymatic resolution yielding L-α-aminoalkanedioic acid ω-esters

DOI: 10.1248/cpb.44.212

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 212 - 214 (1996)

Update date:2022-08-05

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Authors:

Nishino, Norikazu

Arai, Toru

Ueno, Yukio

Ohba, Masataka

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Article abstract of DOI:10.1248/cpb.44.212

The tandem action of serine protease (α-chymotrypsin or subtilisin BPN') and Aspergillus genus aminoacylase on racemic N-acetyl-α-aminoalkanedioic acid α,ω-diester produced L-α-aminoalkanedioic acid ω-ester in good yield and high optical purity. L-α-Amino

Full text of DOI:10.1248/cpb.44.212

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