
Journal of Medicinal Chemistry p. 4408 - 4414 (1992)
Update date:2022-08-04
Topics:
Claudi, Francesco
Giorgioni, Gianfabio
Stefano, Antonio Di
Abbracchio, Maria Pia
Paoletti, Anna Maria
et al.
2-(4-chloro-3-hydroxyphenyl)ethylamine (4) and some derivatives were synthesized as dopamine (DA) receptor ligands.Amine 4 retains the dopaminergic pharmacophore 2-(3-hydroxyphenyl)ethylamine, and the chlorine atom replaces the "para" hydroxyl group of DA
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