Chemistry of Heterocyclic Compounds p. 440 - 444 (1992)
Update date:2022-07-30
Topics:
Shumakov, S. A.
Kaminskii, V. A.
The amination of 3-(2'-oxocyclohexyl)methylcaprolactams and valerolactams with ammonium acetate leads to 3-(ω-aminoalkyl)-3,4,5,6,7,8-hexahydro-2-quinolones.The hydroamination of these keto lactams, as well as their oxocycloheptyl analogs, with a mixture of formamide and formic acid gives 3-(ω-aminoalkyl)perhydro-2-quinolones and 3-(ω-aminoalkyl)-5,6-pentamethylenetetrahydro-2-pyridones.
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Doi:10.1016/j.bmc.2013.05.010
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