Ruthenium(II)-Catalyzed Oxidant-Free C–H Olefination of Aromatic Carboxamides with Allyl Acetate

Article abstract of DOI:10.1002/adsc.201600569

An inexpensive ruthenium-catalyzed direct C–H olefination of aromatic carboxamides with allyl acetate was developed. This external oxidant-free protocol provided an efficient route for the synthesis of useful trans-styrene derivatives in high to excellent yields. The olefination reaction exhibited excellent regioselectivities and allowed the presence of a wide range of functional groups, such as OMe, F, Cl, Br, I, CF₃, NMe₂, as well as NO₂. (Figure presented.).