Synthesis of isoquinoline alkaloids through a 10-membered lactam obtained by radical macrocyclisation

DOI: 10.1016/S0040-4039(00)61171-1

Source and publish data:

Tetrahedron Letters p. 5653 - 5654 (1992)

Update date:2022-08-04

Topics:

Authors:

Lamas, Carlos

Saa, Carlos

Castedo, Luis

Dominguez, Domingo

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)61171-1

A new versatile method for the synthesis of isoquinoline alkaloids 3 and 5 is based on transannular cyclisation of a key macrocycle 2b obtained by an intramolecular addition of an aryl radical to a trimethylsilylacetylene.

Full text of DOI:10.1016/S0040-4039(00)61171-1

Products guided by the article

Product name:Benzamide, N-[2-(2-bromophenyl)ethyl]-2-[(trimethylsilyl)ethynyl]-

Cas No:144631-08-3

R&D Labs maybe for 144631-08-3

Shanghai Pinewood Fine Chemical Co., Ltd.

website:http://www.pinewoodchem.com

Contact:0086-21-62417129，62414096

Address:Suite B, 27F, No.2, Lane 600, Tianshan Road, Shanghai
Cangzhou Senary Chemical Science-tech Co., Ltd

Contact:+86-317-3563899, 3563699

Address:168 Jinde Road, Cangzhou, Hebei, China
Compro Shijiazhuang Fine Chemical Co., Ltd

Contact:0086-311-89689838

Address:Economic and Technological Development Zone of Shijiazhuang,Hebei
Shandong Loyal Chemical industrial Co.,Ltd

Contact:0533-7451788

Address:Linzi Chemical Industrial Park, Zibo, Shandong Province
SuZhou Ascepion Pharmaceuticals, Inc.(expird)

Contact:0512-86881668

Address:Building C,68Xingqing Road,Suzhou,China.

Relevant to this article

A New Xanthone Synthesis from the Diels-Alder Reaction between 2-Vinylchromen-4-ones and Cyclopentanone Enamine

Doi:10.1039/c39920001310
(1992)
Doi:10.1021/ja01505a023
(1960)
Influenza antiviral activity of F- and OH-containing isopulegol-derived octahydro-2H-chromenes

Doi:10.1016/j.bmcl.2020.127677
(2021)
Asymmetric cascade annulation based on enantioselective oxa-diels-alder cycloaddition of in situ generated isochromenyliums by cooperative binary catalysis of Pd(OAc)₂ and (S)-trip

Doi:10.1021/ja405764p
(2013)
115. 1,3-Dipole mit Zentralem S-Atom aus der Umsetzung von Aziden mit Thiocarbonyl-Verbindungen: Eine unerwartete MeS-Wanderung im Abfangprodukt eines 'Thiocarbonyl-aminids' mit Dithiobenzoesaeure-methylester

Doi:10.1002/hlca.19950780609
(1995)
The effect of substrate structure on the chemoselectivity of Candida antarctica lipase B-catalyzed acylation of amino-alcohols

Doi:10.1016/j.molcatb.2012.09.006
(2013)

Article Doi