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Influenza antiviral activity of F- and OH-containing isopulegol-derived octahydro-2H-chromenes

DOI: 10.1016/j.bmcl.2020.127677

Source and publish data:

Bioorganic and Medicinal Chemistry Letters (2021)

Update date:2022-08-04

Topics:

Authors:

Ilyina, Irina V.Ilyina, Irina V.

Patrusheva, Oksana S.Patrusheva, Oksana S.

Zarubaev, Vladimir V.Zarubaev, Vladimir V.

Misiurina, Maria A.Misiurina, Maria A.

Slita, Alexander V.Slita, Alexander V.

Esaulkova, Iana L.Esaulkova, Iana L.

Korchagina, Dina V.Korchagina, Dina V.

Gatilov, Yuri V.Gatilov, Yuri V.

Borisevich, Sophia S.Borisevich, Sophia S.

Volcho, Konstantin P.Volcho, Konstantin P.

Salakhutdinov, Nariman F.Salakhutdinov, Nariman F.

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Article abstract of DOI:10.1016/j.bmcl.2020.127677

We synthesized fluoro- and hydroxy-containing octahydro-2H-chromenes by the Prins reaction starting from a monoterpenoid (–)-isopulegol and a wide range of aromatic aldehydes in the presence of the BF3?Et2O/H2O system acti

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Full text of DOI:10.1016/j.bmcl.2020.127677

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