Biologically active oligodeoxyribonucleotides - II: Structure activity relationships of anti-HIV-1 pentadecadeoxyribonucleotides bearing 5'-end- modifications

Article abstract of DOI:10.1080/15257779408012159

5'-End-modified pentadecadeoxyribonucleotides (15mers) with a sequence complementary to the tat 2nd splicing acceptor region of human immunodeficiency virus type 1 (HIV-1) were prepared and evaluated for anti- HIV-1 activity. The structures of modified 15

Full text of DOI:10.1080/15257779408012159

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Biologically Active
Oligodeoxyribonucleotides - II1:
Structure Activity Relationships of Anti-
HIV-1 Pentadecadeoxyribonucleotides
Bearing 5′-End-Modifications
Hitoshi Hotoda a , Kenji Momota b , Hidehiko Furukawa b , Takemichi
Nakamura c , Masakatsu Kaneko a , Satcshi Kimura d & Kawu Shimada
d
a Exploratory Chemistry Research Laboratories , 1-2-58 Hiromachi,
Shinagawa-ku, Tokyo, 140, Japan
b Biological Research Laboratories , 1-2-58 Hiromachi, Shinagawa-
ku, Tokyo, 140, Japan
c Analytical and Metabolic Research Laboratories, Sankyo Co., Ltd. ,
1-2-58 Hiromachi, Shinagawa-ku, Tokyo, 140, Japan
d The Department of Infectious Diseases , the Institute of Medical
Science, the University of Tokyo , 4-6-1 Shirokanedai, Minato-ku,
Tokyo, 108, Japan
Published online: 24 Sep 2006.
To cite this article: Hitoshi Hotoda , Kenji Momota , Hidehiko Furukawa , Takemichi
Nakamura , Masakatsu Kaneko , Satcshi Kimura & Kawu Shimada (1994) Biologically
Active Oligodeoxyribonucleotides - II1: Structure Activity Relationships of Anti-HIV-1
Pentadecadeoxyribonucleotides Bearing 5′-End-Modifications, Nucleosides and Nucleotides, 13:6-7,
1375-1395, DOI: 10.1080/15257779408012159
To link to this article: http://dx.doi.org/10.1080/15257779408012159
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