Atom economical, one-pot, three-reaction cascade to novel tricyclic 2,4-dihydro-1 H-benzo[ f ]isochromenes

DOI: 10.1021/ol401600j

Source and publish data:

Organic Letters p. 4070 - 4073 (2013)

Update date:2022-09-26

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Authors:

Hinkle, Robert J.

Lewis, Shane E.

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Article abstract of DOI:10.1021/ol401600j

Reaction of 6-methyl-1-phenylhept-3-yne-2,6-diol with various aldehydes under Lewis acid conditions provides an atom economical, two-component cascade reaction sequence to novel 2,4-dihydro-1H-benzo[f]isochromene compounds. Aliphatic aldehydes as well as

Full text of DOI:10.1021/ol401600j

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Product name:2,2-dimethyl-4-(4-nitrophenyl)-2,4-dihydro-1H-benzo[f]isochromene

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