Palladium/chiral amine co-catalyzed enantioselective β-arylation of α,β-unsaturated aldehydes

Article abstract of DOI:10.1002/anie.201208634

Palladium and a simple chiral amine are used as co-catalysts for the enantioselective conjugate addition of aryl boronic acids to α,β-unsaturated aldehydes (see scheme). The synthetic utility of this co-catalyzed reaction was demonstrated in the short tot