Tetrahedron p. 8209 - 8215 (2013)
Update date:2022-09-26
Topics:
George, Ian R.
Lewis, William
Moody, Christopher J.
The total synthesis of the unusual 4-pyridone marine metabolite lodopyridone has been achieved by late stage manipulation of the related 4-pyrone. Key reactions include a Suzuki-Miyaura coupling to form the tetracyclic core and a modified Corey-Ganem-Gilman reaction to install the ethanolamide side-chain.
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