
Journal of Medicinal Chemistry p. 4284 - 4296 (1992)
Update date:2022-08-05
Topics:
Hauske
Dorff
Julin
DiBrino
Spencer
Williams
Small molecule FKBP inhibitors were prepared with inhibitory activity ranging from micromolar to nanomolar. The design of these inhibitors derives from a structural analysis of the substrates for FKBP and cyclophilin. As a consequence of this analysis two
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