Tetrahedron Letters p. 6799 - 6802 (1992)
Update date:2022-09-26
Topics:
Durst, Tony
Koh, Kevin
The reaction of (R)-Pantolactone with α-halogenated ketenes has been found to proceed with good to excellent diastereoselectivities (de 75 to> 95%). The (R)-Pantolacto chiral auxiliary induced the (S)-configuration at the new chiral center in most cases.
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