A convenient N-protection of pyroglutamate derivatives

Article abstract of DOI:10.1080/00397919508011481

Esters of pyroglutamic acid were N-protected by conventional protective groups (Z. Boc, and COOMe) in high yield, without racemization, using LiHMDS in THF at -78°C and ZCl, Boc₂O, and ClCOOMe, respectively.

Full text of DOI:10.1080/00397919508011481

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A Convenient N-Protection of
Pyroglutamate Derivatives
Hao Li a , Takeshi Sakamoto a , Miyako Kato a &
Yasuo Kikugawa a
a Faculty of Pharmaceutical Sciences , Josai
University , Keyakidai 1-1, Sakado, Saitama, 350-02,
Japan
Published online: 23 Sep 2006.
To cite this article: Hao Li , Takeshi Sakamoto , Miyako Kato & Yasuo Kikugawa (1995)
A Convenient N-Protection of Pyroglutamate Derivatives, Synthetic Communications:
An International Journal for Rapid Communication of Synthetic Organic Chemistry,
25:24, 4045-4052, DOI: 10.1080/00397919508011481
To link to this article: http://dx.doi.org/10.1080/00397919508011481
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