Synthesis and cardiovascular activity of phenylalkylamine derivatives. I. Potential specific bradycardic agents

DOI: 10.1248/cpb.40.2735

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2735 - 2740 (1992)

Update date:2022-07-29

Topics:

Authors:

Ozaki Ozaki

Matsukura

Kabasawa

Ishibashi

Ikemori Ikemori

Hamano Hamano

Minami Minami

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Article abstract of DOI:10.1248/cpb.40.2735

A series of acyclic amide derivatives of N-(ω-aminoalkyl)-N-methylhomoveratrylamine was synthesized and evaluated for their bradycardic activity in isolated guinea pig right atria. Among these compounds, (E)-N-[3[N'-[2-(3,4-dimethoxyphenyl)ethyl]-N'-methy

Full text of DOI:10.1248/cpb.40.2735

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