Synthesis and pharmacological activities of novel bicyclic thiazoline derivatives as hepatoprotective agents. I. 8-Ethoxycarbonyl-5,6-dilhydrothiazolo [2,3-c][1,4]thiazine derivatives

DOI: 10.1248/cpb.43.78

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 78 - 83 (1995)

Update date:2022-08-05

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Authors:

Hasegawa

Nakayama

Hosokami

Kurebayashi

Ikeda Ikeda

Shimoto Shimoto

Ide Ide

Honde Honde

Suzuki Suzuki

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Article abstract of DOI:10.1248/cpb.43.78

A series of bicyclic thiazoline derivatives (4a-s) was synthesized and evaluated for hepatoprotective activity against galactosamine-induced and monoclonal antibody-induced acute liver injuries in rats. The structure-activity relationships were investigat

Full text of DOI:10.1248/cpb.43.78

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