Peptide-Based Nucleic Acid Surrogates Incorporating Ser-Gly Subunits

Article abstract of DOI:10.1016/S0040-4039(00)91773-8

The synthesis of building blocks corresponding to four natural nucleobases (A, C, G, and T) is presented and it is demonstrated that such units may be linked together using standard peptide coupling techniques without racemization or β-elimination.