Oligonucleotides Derived from 5-(1-Propynyl)-2'-O-Allyl-Uridine and 5-(1-Propynyl)-2'-O-Allyl-Cytidine: Synthesis and RNA Duplex Formation

Article abstract of DOI:10.1016/S0040-4039(00)77476-4

The protected nucleoside analogs of 5-(1-propynyl)-2'-O-allyl-uridine and 5-(1-propynyl)-2'-O-allyl-cytidine are described.Oligonucleotides containing this modification significantly enhance double-helix formation with single-strand RNA.