Pd/Cu Cocatalyzed Oxidative Tandem C-H Aminocarbonylation and Dehydrogenation of Tryptamines: Synthesis of Carbolinones

DOI: 10.1021/acs.joc.8b03266

Source and publish data:

Journal of Organic Chemistry p. 3357 - 3369 (2019)

Update date:2022-09-26

Topics:

Authors:

Han, Hui

Xia, Ji-Bao

Yang, Shang-Dong

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/acs.joc.8b03266

The Pd/Cu cocatalyzed oxidative tandem C-H aminocarbonylation and dehydrogenation was developed, affording carbolinones with molecular oxygen as the terminal oxidant. Natural product strychnocarpine and its derivatives were prepared conveniently using this strategy.

Full text of DOI:10.1021/acs.joc.8b03266

Products guided by the article

Product name:2-(1H-indol-1-yl)-N-methylethanamine(SALTDATA: oxalate)

Cas No:148806-52-4

R&D Labs maybe for 148806-52-4

Hunan Haili Chemical Industry Co.,Ltd.

Contact:+86-731-85521860

Address:No.251, 2nd Section, Furong Road, Changsha,Hunan,China
Dongguan Albiya Energy Science and Technology Co.,Ltd

Contact:+86-769-22181286

Address:Huanan Industial Park, Dongguan,China
Zhangjiagang Golden Reach Fine Chemical Co.,LTD.

Contact:+86-512-6585 6968

Address:Changfu Road， Dongsha Chemical Industry Park, Zhangjiagang City, Jiangsu Province, China
Hangzhou Think Chemical Co. Ltd

website:http://www.thinkchem.com/

Contact:86-571-89986307/81956191/81956084/81956192

Address:Room 501-502, Tower E, Yuanjian Building, Yuanyang International Center, Hangzhou-310011, China
Sichuan Sangao Biochemical Co., Ltd

Contact:+86-28-84874233

Address:19F, Bldg.2, Shudu Center, Tianfu 2nd St., Hi-tech zone, Chengdu 610041, Sichuan Province, China.

Relevant to this article

CB 1/2 dual agonists with 3-carbamoyl 2-pyridone derivatives as antipruritics: Reduction of CNS side effects by introducing polar functional groups

Doi:10.1016/j.bmcl.2012.02.054
(2012)
Synthesis and Desymmetrization of meso Tricyclic Systems Derived from Benzene Oxide

Doi:10.1021/acs.joc.8b00523
(2018)
Discotic triphenylene twins linked through thiophene bridges: Controlling nematic behavior in an intriguing class of functional organic materials

Doi:10.1021/jo3002886
(2012)
Unusual NHC-Iridium(I) Complexes and Their Use in the Intramolecular Hydroamination of Unactivated Aminoalkenes

Doi:10.1002/chem.201600378
(2016)
Enantiospecific total synthesis of 15-hydroxy-5-(methoxymethoxy) crinipellin-9-one

Doi:10.1016/j.tet.2012.02.018
(2012)
Asymmetric Catalytic Enantio- and Diastereoselective Boron Conjugate Addition Reactions of α-Functionalized α,β-Unsaturated Carbonyl Substrates

Doi:10.1021/acs.orglett.6b01998
(2016)

Article Doi