A SIMPLE AND EFFECTIVE ENANTIOMERIC SYNTHESIS OF A CHIRAL PRIMARY AMINE

Article abstract of DOI:10.1016/S0040-4039(00)77588-5

Catalytic reduction of chiral 2-(2-pyridyl)-1,3-oxazolidines and 2-pyridyl imines derived from (R)-phenylglycinol and (R)-valinol afforded high diastereomeric selectivity.Upon oxidative cleavage, the S-primary amine with high ee was obtained.