Total synthesis of the naturally occurring antibiotic toyocamycin using new and improved synthetic procedures

Article abstract of DOI:10.1080/15257779908043063

Starting with commercially available tetracyanoethylene, we describe a more efficient and higher yielding synthesis of toyocamycin with regards to convenience, overall yield, and total reaction time than those syntheses previously reported.

Full text of DOI:10.1080/15257779908043063

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Nucleosides and Nucleotides
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Total Synthesis of the Naturally
Occurring Antibiotic Toyocamycin Using
New and Improved Synthetic Procedures
Anthony R. Porcari a & Leroy B. Townsend a
a Department of Medicinal Chemistry, College of Pharmacy;
Department of Chemistry , College of Literature, Science, and Arts,
University of Michigan , Ann Arbor, Michigan, 48109-1065
Published online: 04 Oct 2006.
To cite this article: Anthony R. Porcari & Leroy B. Townsend (1999) Total Synthesis of the Naturally
Occurring Antibiotic Toyocamycin Using New and Improved Synthetic Procedures, Nucleosides and
Nucleotides, 18:2, 153-159, DOI: 10.1080/15257779908043063
To link to this article: http://dx.doi.org/10.1080/15257779908043063
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