Steric tuning in chiral ligand mediated enantioselective alkylation of imines

DOI: 10.1016/S0957-4166(00)80366-3

Source and publish data:

Tetrahedron Asymmetry p. 1603 - 1606 (1993)

Update date:2022-07-29

Topics:

Authors:

Inoue Inoue

Shindo Shindo

Koga Koga

Tomioka Tomioka

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Article abstract of DOI:10.1016/S0957-4166(00)80366-3

Enantioselective alkylation of achiral aldimines 4 prepared from 2-methylanisidine with organolithiums was mediated by a chiral aminoether 1 to give the corresponding amines 5 in high ee.

Full text of DOI:10.1016/S0957-4166(00)80366-3

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Product name:(4-Methoxy-2-methyl-phenyl)-[1-phenyl-meth-(E)-ylidene]-amine

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