Selective Synthesis of the Geometrical Isomers of O,O-Diethyl O-1-(N-methoxyimino)ethylphosphorothioate and a New Thiono-Thiolo Rearrangement Reaction

Article abstract of DOI:10.1246/cl.1993.1835

Condensation of O,O-diethyl phosphorochloridothioate with N-methoxyacetamide in the presence of a base gave selectively the geometrical isomers of O,O-diethyl O-1-(N-methoxyimino)ethylphosphorothioate which on heating rearranged to the corresponding thiolo isomers having P-S-C=N linkage.