
Tetrahedron Letters p. 8159 - 8162 (1993)
Update date:2022-09-26
Topics:
Golec, Julian M. C.
Jones, Stuart D.
The asymmetric synthesis of a fragment corresponding to the C1-C8 region of the immunosuppressant discodermolide is reported.A trihydroxylactone of defined absolute stereochemistry is also prepared.This compound is a potential reductive ozonolysis product of discodermolide and may aid the determination of the absolute stereochemistry of the natural product.
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