A facile synthesis of 5-phenylimidazo-[4,5-c] [1,8]naphthyridin-4(5H)-one

Article abstract of DOI:10.1080/00397919408010252

1-Phenyl-3-nitroso-4-amino-1,8-naphthyridin-2(1H)-one (9) was prepared on a large scale and was converted to 5-phenyl-imidazo[4,5-c] [1,8]naphthyridin-4(5H)-one (KF17625, 1) which exhibitis potent antiasthmatic activity.

Full text of DOI:10.1080/00397919408010252

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Synthetic Communications: An
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A Facile Synthesis of 5-
Phenylimidazo- [4,5-c]-
[1,8]naphthyridin-4(5H)-one
Yukihiro Kuge a , Nobuyuki Kato a , Toru Sugaya a &
Shinji Tomioka a
a Sakai Research Laboratories, Kyowa Hakko Kogyo
Co. Ltd., 1-1-53, Takasu-cho, Sakai-shi, Osaka, 590,
Japan
Available online: 23 Sep 2006
To cite this article: Yukihiro Kuge, Nobuyuki Kato, Toru Sugaya & Shinji Tomioka
(1994): A Facile Synthesis of 5-Phenylimidazo- [4,5-c]-[1,8]naphthyridin-4(5H)-one,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 24:22, 3289-3296
To link to this article: http://dx.doi.org/10.1080/00397919408010252
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