Convenient syntheses of optically active β-lactams by enzymatic resolution

DOI: 10.1248/cpb.41.1933

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1933 - 1938 (1993)

Update date:2022-08-02

Topics:

Authors:

Nagai Nagai

Shiozawa

Achiwa Achiwa

Terao Terao

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Article abstract of DOI:10.1248/cpb.41.1933

Optically active β-lactams were synthesized by lipase-catalyzed kinetic resolution using the enantioselective hydrolysis of N-acyloxymethyl β- lactams (3) in an organic solvent and the transesterification of N- hydroxymethyl β-lactams (2) with vinyl aceta

Full text of DOI:10.1248/cpb.41.1933

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