Tetrahedron Letters p. 1377 - 1380 (1998)
Update date:2022-08-04
Topics:
Sugahara, Masakatsu
Moritani, Yasunori
Terakawa, Yoshihiro
Ogiku, Tsuyoshi
Ukita, Tatsuzo
Iwasaki, Tameo
A new series of 1-arylnaphthalene lignan analogs having a variety of pyridyl substituents at the C-1 position were synthesized in moderate to good yields by means of the Diels-Alder reaction by utilizing 1-pyridylisobenzofuran precursors with dimethyl fumarate, methyl acrylate, or dimethyl acetylene dicarboxylate, followed by BF3·Et2O-mediated aromatization.
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