Synthesis of a B-homo 6-azaandrost-4-ene-3-one as a novel steroidal 5α- reductase inhibitor

DOI: 10.1016/S0040-4039(00)76634-2

Source and publish data:

Tetrahedron Letters p. 2823 - 2826 (1994)

Update date:2022-09-26

Topics:

Authors:

Maloney Maloney

Fang Fang

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)76634-2

The preparation of a B-ring homologated analog of 17β-N,N- diethylcarboxy-6-azaandrost-4-ene-3-one, a potent inhibitor of type 2 steroidal 5α-reductase, is described.

Full text of DOI:10.1016/S0040-4039(00)76634-2

Products guided by the article

Product name:(1S,3aS,4S,5S,7aS)-7a-Methyl-5-((1R,4S)-1-methyl-2-oxo-4-triisopropylsilanyloxy-cyclohexyl)-4-(2-oxo-ethyl)-octahydro-indene-1-carboxylic acid diethylamide

Cas No:155913-46-5

R&D Labs maybe for 155913-46-5

HUNAN OUYA BIOLOGICAL CO.,LTD

Contact:+8613400661290

Address:No 908,Kangwan Rd, Liuyang Economic
NOVASYNCS CO., LTD

Contact:0512-63006287

Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA
Sichuan Highlight Fine Chemicals Co., Ltd.

Contact:+86-28-8525 1605

Address:A5-102 Airport base,388 West Airport Huang He Zhong Lu,2 Section
Shanghai Haoyuan Chemexpress Co., Ltd.

website:https://www.chemexpress.com/

Contact:86-21-58950125

Address:No.3 Building, No.1999, Zhangheng Road, ZhangjiangHighTech Park, Shanghai, P.R.China,201203
Zhangjiagang Golden Reach Fine Chemical Co.,LTD.

Contact:+86-512-6585 6968

Address:Changfu Road， Dongsha Chemical Industry Park, Zhangjiagang City, Jiangsu Province, China

Relevant to this article

Metal- and Reagent-Free Dehydrogenative Formal Benzyl–Aryl Cross-Coupling by Anodic Activation in 1,1,1,3,3,3-Hexafluoropropan-2-ol

Doi:10.1002/anie.201804997
(2018)
Hetero-Tetradehydro-Diels-Alder Cycloaddition of Enynamides and Cyanamides: Gold-Catalyzed Generation of Diversely Substituted 2,6-Diaminopyridines

Doi:10.1021/acs.joc.1c00558
(2021)
Enantioselective Synthesis of Chiral α-Azido and α-Aryloxy Quaternary Stereogenic Centers via the Phase-Transfer-Catalyzed α-Alkylation of α-Bromomalonates, Followed by S_N2 Substitution

Doi:10.1021/acs.joc.7b00324
(2017)
Water soluble furoxan derivatives as NO prodrugs

Doi:10.1021/jm960379t
(1997)
Synthesis of P-chiral, phosphorothioic acid analogs of N-phospholeucinamide

Doi:10.1016/S0040-4039(96)02107-7
(1996)
Selective N-alkylation of pyrrolopyrimidines and indoles by 'transfer of activation'

Doi:10.1016/S0040-4039(98)01146-0
(1998)

Article Doi