Journal of Organic Chemistry p. 3243 - 3245 (1994)
Update date:2022-08-03
Topics:
Davis, Franklin A.
Zhou, Ping
Reddy, G. Venkat
cis-Aziridine-2-carboxylic acids, 2, precursors of the difficult to prepare syn-β-hydroxy-α-amino acid structural unit, are prepared in high diastereomeric purity by a Darzens-type reaction of the lithium enolate of methyl bromoacetate with enantiopure sulfinimines 1.
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