Polycyclic propargylamine and acetylene derivatives as multifunctional neuroprotective agents

DOI: 10.1016/j.ejmech.2014.04.039

Source and publish data:

European Journal of Medicinal Chemistry p. 122 - 134 (2014)

Update date:2022-07-29

Topics:

Authors:

Zindo, Frank T.

Barber, Quinton R.

Joubert, Jacques

Bergh, Jacobus J.

Petzer, Jacobus P.

Malan, Sarel F.

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Article abstract of DOI:10.1016/j.ejmech.2014.04.039

The aim of this study was to design drug-like molecules with multiple neuroprotective mechanisms which would ultimately inhibit N-methyl-d-aspartate (NMDA) receptors, block L-type voltage gated calcium channels (VGCC) and inhibit apoptotic processes as we

Full text of DOI:10.1016/j.ejmech.2014.04.039

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