SYNTHESIS OF ADAMANTYL-SUBSTITUTED PYRAZOLINES

Article abstract of DOI:10.1007/BF01165025

The reaction of a series of N-R-N-R¹-1(β-aminopropionyl)adamantanes with phenylhydrazine formed 3-(adamantyl-1)-1-phenylpyrazoline, the structure of which was confirmed by reverse synthesis from adamantyl-1-vinyl ketone.It is shown that the nitroso derivative of the secondary β-amino ketone is also cyclized into 3-(adamantyl-1)-1-phenylpyrazoline.