
Synthesis p. 1249 - 1254 (1994)
Update date:2022-08-03
Topics: Synthesis Compounds Stereocontrolled Synthesis Experimental terms Chemical terms
Watanabe
Shimizu
Mori
A stereocontrolled synthesis of (+)-juvabione is described. The key step is a regioselective lithiation of a chiral (E)-butenyl sulfoxide 5 followed by stereoselective 1,4-addition to cyclohex-2-en-1-one. The chiral sulfoxide 5 was prepared by employing a
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