162329-01-3Relevant academic research and scientific papers
Synthesis of compounds with juvenile hormone activity; XXXI: Stereocontrolled synthesis of (+)-juvabione from a chiral sulfoxide
Watanabe,Shimizu,Mori
, p. 1249 - 1254 (1994)
A stereocontrolled synthesis of (+)-juvabione is described. The key step is a regioselective lithiation of a chiral (E)-butenyl sulfoxide 5 followed by stereoselective 1,4-addition to cyclohex-2-en-1-one. The chiral sulfoxide 5 was prepared by employing a
