Journal of the American Chemical Society p. 2409 - 2420 (1995)
Update date:2022-07-30
Topics: Chemical Synthesis Biological Evaluation experimentation C-2 taxoids
Nicolaou
Renaud
Nantermet
Couladouros
Guy
Wrasidlo
An efficient, general method for the synthesis of 1,2-hydroxy esters by regioselective nucleophilic opening of 1,2-cyclic carbonate systems has been developed. A reliable and practical route giving access to the taxoid carbonate 2 from the readily availab
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