Chemical synthesis and biological evaluation of C-2 taxoids

DOI: 10.1021/ja00114a005

Source and publish data:

Journal of the American Chemical Society p. 2409 - 2420 (1995)

Update date:2022-07-30

Topics: Chemical Synthesis Biological Evaluation experimentation

Authors:

Nicolaou

Renaud Renaud

Nantermet

Couladouros

Guy Guy

Wrasidlo

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Article abstract of DOI:10.1021/ja00114a005

An efficient, general method for the synthesis of 1,2-hydroxy esters by regioselective nucleophilic opening of 1,2-cyclic carbonate systems has been developed. A reliable and practical route giving access to the taxoid carbonate 2 from the readily availab

Full text of DOI:10.1021/ja00114a005

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