Novel open-chain nucleotides imitating 2',3'-dideoxy-2',3'- didehydronucleotides: Synthesis and substrate properties toward DNA polymerases

Article abstract of DOI:10.1080/15257779508012464

A new series of acyclic nucleotide diphosphates was synthesized and evaluated as potential inbibitors of HIV reverse transcriptases.

Full text of DOI:10.1080/15257779508012464

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Novel Open-Chain Nucleotides
Imitating 2′,3′-Dideoxy-2′,3′-
Didehydronucleotides: Synthesis and
Substrate Properties Toward DNA
Polymerases
E. A. Shirokova a , N. B. Tarussova a , A. V. Shipitsin a , D. G.
Semizarov a , M. Hieber a b & A. A. Krayevsky a
a Engelhardt Institute of Molecular Biology Russian Academy of
Sciences , 32 Vavilov st., Moscow, 117984, Russia
b Universitat des Saarlandes im Stadwald , 66123, Saarbrucken,
Germany
Published online: 16 Feb 2007.
To cite this article: E. A. Shirokova , N. B. Tarussova , A. V. Shipitsin , D. G. Semizarov , M.
Hieber & A. A. Krayevsky (1995) Novel Open-Chain Nucleotides Imitating 2′,3′-Dideoxy-2′,3′-
Didehydronucleotides: Synthesis and Substrate Properties Toward DNA Polymerases, Nucleosides and
Nucleotides, 14:3-5, 749-751
To link to this article: http://dx.doi.org/10.1080/15257779508012464
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