A Novel Bicyclic Orthoester as a Chiral Auxiliary: Application to the Synthesis of α-Hydroxy Acids

DOI: 10.1016/0040-4039(95)00154-5

Source and publish data:

Tetrahedron Letters p. 1827 - 1830 (1995)

Update date:2022-07-31

Topics:

Authors:

Dube, D.

Deschenes, D.

Tweddell, J.

Gagnon, H.

Carlini, R.

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Article abstract of DOI:10.1016/0040-4039(95)00154-5

Chiral α-keto orthoesters derived from tartanic acid can be reduced diastereoselectively.Hydrolysis affords optically actice α-hydroxy acids and the recovered auxiliary.

Full text of DOI:10.1016/0040-4039(95)00154-5

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