Bismurrayaquinone A: Synthesis, Chromatographic Enantiomer Resolution, and Stereoanalysis by Computational and Experimental CD Investigations

Article abstract of DOI:10.1016/0040-4020(95)00528-G

The first total synthesis of a naturally occurring dimeric carbazole alkaloid, bismurrayaquinone A (4), is described, by oxidation of dimeric O-demethylmurrayafoline A, a still hypothetic natural product recently synthesized.By chromatography on a chiral phase, the two atropoenantiomers were separated.The absolute configurations of these two rotational isomers were elucidated by comparison of their calculated spectra with those measured experimentally.