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58-56-0

Basic Information
CAS No.: 58-56-0
Name: Pyridoxine hydrochloride
Molecular Structure:
Molecular Structure of 58-56-0 (Pyridoxine hydrochloride)
Formula: C8H11NO3.ClH
Molecular Weight: 205.64 .
Synonyms: 3,4-Pyridinedimethanol,5-hydroxy-6-methyl-, hydrochloride (9CI);Pyridoxol, hydrochloride (7CI,8CI);2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine hydrochloride;4,5-Bis(hydroxymethyl)-2-methylpyridin-3-olhydrochloride;4,5-Bis(hydroxymethyl)-3-hydroxy-2-methylpyridine hydrochloride;5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride;Aderomine hydrochloride;Aderoxin;Aderoxine;Hexabetalin;Hexavibex;Pyridipca;Pyridox;Pyridoxin hydrochloride;Pyridoxine chloride;
EINECS: 200-386-2
Density: 1.2784 (rough estimate)
Melting Point: 214-215 °C(lit.)
Boiling Point: 491.9 °C at 760 mmHg
Flash Point: 251.3 °C
Solubility: 0.1 g/mL at 20 °C in water
Appearance: Crystalline
Hazard Symbols: IrritantXi
Risk Codes: 36/37/38
Safety: 26-37/39
Transport Information:
PSA: 73.58000
LogP: 0.88220
Synthetic route
10030-93-0

pyridoxine triacetate

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water for 2h; Heating;98%
With hydrogenchloride; water for 2h; Heating / reflux;72%
2397-71-9

5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid diethyl ester

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 5-hydroxy-6-methylpyridine-3,4-dicarboxylic acid diethyl ester With sodium tetrahydroborate; iron(II) sulfate; N,N-dimethyl-aniline In tetrahydrofuran for 4h; Reflux;
Stage #2: With hydrogenchloride In tetrahydrofuran at 20℃; Reagent/catalyst; Solvent;
93.4%

4,5-dihydroxymethyl-2-methyl-2-cyclopentenone

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 4,5-dihydroxymethyl-2-methyl-2-cyclopentenone With ozone In methanol; water at -30℃; for 3h;
Stage #2: With ammonia In methanol; water at 20 - 25℃; for 3h;
Stage #3: With hydrogenchloride; pyrographite In ethanol at 55 - 60℃; for 1h; Temperature; Solvent;
92%

2-hydroxymethyl-3-cyano-4-hydroxy-n-butyraldehyde

13515-97-4

methyl 2-aminopropanoate monohydrochloride

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 2-hydroxymethyl-3-cyano-4-hydroxy-n-butyraldehyde; methyl 2-aminopropanoate monohydrochloride With sodium methylate In methanol at 30 - 50℃; for 5h; Green chemistry;
Stage #2: With hydrogenchloride In methanol; water for 2h; Temperature; Solvent; Reagent/catalyst; Reflux; Green chemistry;
90.5%

4-methyl-5-dimethyl-tert-butylsiloxyoxazole

4469-34-5

2-propyl-4,7-dihydro-2H-1,3-dioxepine

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 4-methyl-5-dimethyl-tert-butylsiloxyoxazole; 2-propyl-4,7-dihydro-2H-1,3-dioxepine at 115 - 120℃; for 10h;
Stage #2: With water In ethanol at 20℃; for 3h;
Stage #3: With hydrogenchloride In ethanol; water at 20℃; for 2h;
89.5%
5205-63-0

Diels-Alder adduct

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: Diels-Alder adduct With hydrogenchloride In ethanol; water at 20℃; for 2h;
Stage #2: In ethanol; water for 2h;
86.05%

C8H13NO4

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; pyrographite In ethanol; water at 75 - 78℃; for 3h; Temperature;83.5%

4-methyl-5-triisopropylsiloxyoxazole

4469-34-5

2-propyl-4,7-dihydro-2H-1,3-dioxepine

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 4-methyl-5-triisopropylsiloxyoxazole; 2-propyl-4,7-dihydro-2H-1,3-dioxepine at 115 - 120℃; for 10h;
Stage #2: With water In ethanol at 20℃; for 3h;
Stage #3: With hydrogenchloride In ethanol; water at 20℃; for 2h;
82.7%
4469-34-5

2-propyl-4,7-dihydro-2H-1,3-dioxepine

24201-52-3

4-methyl-5-butoxy1,3-oxazole

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Stage #1: 2-propyl-4,7-dihydro-2H-1,3-dioxepine; 4-methyl-5-butoxy1,3-oxazole With calcium oxide at 150℃; for 12h; Diels-Alder Cycloaddition;
Stage #2: With hydrogenchloride In ethanol; water at 20 - 60℃; for 12h;
Stage #3: With hydrogenchloride In water for 1h; pH=8; Reagent/catalyst; Reflux;
80%
5006-20-2

5-ethoxy-4-methyl-oxazole

4469-34-5

2-propyl-4,7-dihydro-2H-1,3-dioxepine

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With hydrogenchloride Diels-Alder Cycloaddition;78.5%
90330-16-8

3-amino-4,5-bis(aminomethyl)2-methylpyridine trihydrochloride

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With sulfuric acid; sodium nitrite In water at 90℃; for 2h;75%
39984-49-1

2-Methyl-3-hydroxy-4,5-bis-(bromomethyl)-pyridine hydrobromide

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With water; silver(I) chloride for 0.333333h; Heating;68%
Multi-step reaction with 2 steps
1: 2.) AcONa / 1.) DMF, 55 degC, 1 h; 2.) DMF, 85 degC, 2.5 h
2: 98 percent / 2N HCl / H2O / 2 h / Heating
View Scheme
524-36-7

pyridoxamine dihydrochloride

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With sulfuric acid; water; sodium nitrite at 20 - 90℃; for 2h;25%
67-03-8

Thiamine hydrochloride

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With N-Bs In isopropyl alcohol at 25℃; for 0.5h;
80095-36-9

L-1-Deoxy<1,1,1-(2)H3,(RS)-5-(2)H1>xylulose

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With D-glucose; Escherichia coli B WG2 Mechanism;
83537-53-5

3-amino-4-aminomethyl-5-hydroxymethyl-2-methylpyridine dihydrochloride

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With cis-nitrous acid In water at 90℃;

Acetic acid 4-acetoxymethyl-2,5-dimethoxy-2-(1-methoxycarbonylamino-ethyl)-2,5-dihydro-furan-3-ylmethyl ester

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In water Yield given;
7647-01-0

hydrogenchloride

45996-87-0

4,5-bis-aminomethyl-2-methyl-pyridin-3-ol

aqueous NaNO2

aqueous NaNO2

A

58-56-0

pyridoxal hydrochloride

B

<5-chloromethyl>-3-hydroxy-2-methyl-<4>pyridyl>-methanol

<5-chloromethyl>-3-hydroxy-2-methyl-<4>pyridyl>-methanol

7647-01-0

hydrogenchloride

4-ethoxymethyl-5-hydroxymethyl-2-methyl-pyridin-3-ol; hydrochloride

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
at 155 - 160℃;
71058-42-9

5-amino-6-methylpyridine-3,4-dicarbonitrile

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 75 percent / conc. HCl, H2 / 5 percent Pd-C / methanol; H2O / 3.5 h / Ambient temperature
2: 75 percent / sodium nitrite, H2SO4 / H2O / 2 h / 90 °C
View Scheme
83537-57-9

5-acetoxymethyl-3-amino-2-methylpyridine-4-carbonitrile

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 88 percent / 1) conc. HCl, H2; 2) 0.2 N HCl / 1) 5 percent Pd-C / methanol; H2O / 1) 1 h, RT; 2) 1 h, 80 deg C
2: nitrous acid / H2O / 90 °C
View Scheme
14496-24-3

3,4-bis(hydroxymethyl)furan

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 100 percent / pyridine
2: 57 percent / p-toluenesulfonic acid / 2 h / 0 - 5 °C
3: electrochemical oxidation
4: HCl / H2O
View Scheme
30614-73-4

3,4-furan dimethanol diacetate

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 57 percent / p-toluenesulfonic acid / 2 h / 0 - 5 °C
2: electrochemical oxidation
3: HCl / H2O
View Scheme
79588-15-1

Acetic acid 4-acetoxymethyl-2-(1-methoxycarbonylamino-ethyl)-furan-3-ylmethyl ester

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: electrochemical oxidation
2: HCl / H2O
View Scheme
104307-94-0

1,3-dihydro-6-methyl-7-iodofuro(3,4-c)pyridine

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 36 percent / Na, MeOH / CuI2 / various solvent(s) / 16 h / Heating
2: 78 percent / 48percent HBr / 2 h / Heating
3: 68 percent / H2O, AgCl / 0.33 h / Heating
View Scheme
104307-95-1

1,3-dihydro-6-methyl-7-methoxyfuro(3,4-c)pyridine

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 78 percent / 48percent HBr / 2 h / Heating
2: 68 percent / H2O, AgCl / 0.33 h / Heating
View Scheme
104307-93-9

1,3-dihydro-6-methyl-7-trimethylstannylfuro(3,4-c)pyridine

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 99 percent / I2 / CHCl3 / 18 h / Ambient temperature
2: 36 percent / Na, MeOH / CuI2 / various solvent(s) / 16 h / Heating
3: 78 percent / 48percent HBr / 2 h / Heating
4: 68 percent / H2O, AgCl / 0.33 h / Heating
View Scheme
1622-67-9

4,5'-O-isobutylidenepyridoxine

58-56-0

pyridoxal hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; water under 300.03 Torr; for 2h; Product distribution / selectivity; Heating / reflux;
Stage #1: 4,5'-O-isobutylidenepyridoxine With hydrogenchloride; water In tetrahydrofuran at 60 - 120℃; under 150.015 Torr; for 3h;
Stage #2: With pyrographite In water at 0 - 60℃; Product distribution / selectivity;
717916-87-5

3-isopropyl-1,5-dihydro[1,3]dioxepino-3-methyl-4-n-butoxy-7-oxa-2-azabicyclo[2.2.1]hept-2-ene

A

58-56-0

pyridoxal hydrochloride

B

1622-67-9

4,5'-O-isobutylidenepyridoxine

Conditions
ConditionsYield
Stage #1: 3-isopropyl-1,5-dihydro[1,3]dioxepino-3-methyl-4-n-butoxy-7-oxa-2-azabicyclo[2.2.1]hept-2-ene With water; acetic acid In tetrahydrofuran at 60℃; under 760.051 Torr; for 4h;
Stage #2: With hydrogenchloride; water In tetrahydrofuran at 0 - 60℃; for 5h; Product distribution / selectivity;
Stage #1: 3-isopropyl-1,5-dihydro[1,3]dioxepino-3-methyl-4-n-butoxy-7-oxa-2-azabicyclo[2.2.1]hept-2-ene With water In tetrahydrofuran at 60℃; under 760.051 Torr; for 4h;
Stage #2: With hydrogenchloride In tetrahydrofuran at 20 - 60℃; for 5h; Product distribution / selectivity;
concentrated H2 SO4

concentrated H2 SO4

58-56-0

pyridoxal hydrochloride

isopropylidene pyridoxine

Conditions
ConditionsYield
In acetone100%
58-56-0

pyridoxal hydrochloride

39984-50-4

4,5-bis(chloromethyl)-3-hydroxy-2-methylpyridinium chloride

Conditions
ConditionsYield
With thionyl chloride In N,N-dimethyl-formamide for 0.5h; Reflux; Inert atmosphere;99%
With thionyl chloride In dichloromethane; N,N-dimethyl-formamide for 12h; Reflux;96%
With thionyl chloride; N,N-dimethyl-formamide at 80℃; for 3h;93%
58-56-0

pyridoxal hydrochloride

121-57-3

4-aminobenzene sulfonic acid

1122445-21-9

C14H14N2O5S

Conditions
ConditionsYield
Stage #1: pyridoxal hydrochloride With RuCl2(PPh3)2(BAOBEA); dihydrogen peroxide In water at 60℃; for 0.25h;
Stage #2: 4-aminobenzene sulfonic acid In water for 0.0833333h; Reflux;
98.25%
58-56-0

pyridoxal hydrochloride

77-76-9

2,2-dimethoxy-propane

1136-52-3

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol

Conditions
ConditionsYield
With toluene-4-sulfonic acid In acetone at 20℃;98%
With toluene-4-sulfonic acid In acetone at 20℃; for 23h;96%
With toluene-4-sulfonic acid In acetone at 20℃; for 23h;96%
With toluene-4-sulfonic acid In acetone at 20℃; for 20h; Inert atmosphere;86%
With toluene-4-sulfonic acid In water; acetone for 20h; Inert atmosphere;80%
58-56-0

pyridoxal hydrochloride

108-24-7

acetic anhydride

10030-93-0

pyridoxine triacetate

Conditions
ConditionsYield
With triethylamine In tert-butyl methyl ether at 50 - 65℃; for 2.5h; Industry scale; Heating / reflux;96%
With pyridine Ambient temperature;57%
With pyridine
58-56-0

pyridoxal hydrochloride

108-24-7

acetic anhydride

53580-75-9

2,4-dimethyl-5-acetoxymethylpyridin-3-ol

Conditions
ConditionsYield
With zinc for 2h; Reflux;95%

cobalt(II) chloride hexahydrate

617-65-2

Glutamic acid

58-56-0

pyridoxal hydrochloride

Co(2+)*C5HN(CH3)(O)(CH2OH)2(1-)*OOCCH2CH2(NH2)CHCOO(2-)*H(1+)*3H2O=Co{C5HN(CH3)(O)(CH2OH)2}(C5H8NO4)*3H2O

Conditions
ConditionsYield
With lithium carbonate In water byproducts: CO2; to soln. pyridoxine/water was added equimolar amt. glutamic acid and excess Li2CO3, after evolution CO2 completed addn. equimolar soln. CoCl2/H2O, formation of pink ppt.; ppt. separated, washed (EtOH and ether) until powdery, elem. anal.;94.4%
58-56-0

pyridoxal hydrochloride

148-51-6

3-hydroxy-5-hydroxymethyl-2,4-dimethylpyridinium chloride

Conditions
ConditionsYield
Stage #1: pyridoxal hydrochloride With acetic acid; zinc for 12h; Reflux;
Stage #2: With hydrogenchloride In methanol at 0℃; for 2h;
94%
Stage #1: pyridoxal hydrochloride With acetic acid; zinc for 12h; Reflux;
Stage #2: With hydrogenchloride In methanol; water at 0℃; for 2h;
94%
With acetic acid; zinc for 24h; Reflux;94%
Stage #1: pyridoxal hydrochloride With acetic acid; zinc at 120℃; for 3h;
Stage #2: With hydrogenchloride In methanol at 60℃; for 1h;
93%
Multi-step reaction with 2 steps
1: zinc / 72 h / Reflux
2: hydrogenchloride / water / 8 h / 50 °C
View Scheme
58-56-0

pyridoxal hydrochloride

102694-13-3

4,5-bis-chloromethyl-2-methyl-pyridin-3-ol

Conditions
ConditionsYield
With thionyl chloride In N,N-dimethyl-formamide for 0.5h; Reflux;93%
With thionyl chloride In N,N-dimethyl-formamide for 0.5h; Inert atmosphere; Reflux;93%
58-56-0

pyridoxal hydrochloride

77-76-9

2,2-dimethoxy-propane

A

1136-52-3

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol

B

948-00-5

1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol

Conditions
ConditionsYield
With sulfuric acid In dichloromethane for 6h; Heating;A 92%
B n/a
58-56-0

pyridoxal hydrochloride

A

948-00-5

1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol

B

77-76-9

2,2-dimethoxy-propane

Conditions
ConditionsYield
With sulfuric acid In dichloromethane for 6h; Heating; Title compound not separated from byproducts;A n/a
B 92%
58-56-0

pyridoxal hydrochloride

67-64-1

acetone

6953-28-2

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol hydrochloride

Conditions
ConditionsYield
With hydrogenchloride92%
With hydrogenchloride for 2.5h;90.9%
With hydrogenchloride at 20 - 30℃; for 6h;85%
With hydrogenchloride HCl introduction below 10 degC, then -10 degC, overnight;54%
With hydrogenchloride at 0℃; for 2h;27.3 g
58-56-0

pyridoxal hydrochloride

67-64-1

acetone

1136-52-3

(2,2,8-trimethyl-4H-[1,3]dioxino[4,5-c]pyridin-5-yl)methanol

Conditions
ConditionsYield
With thionyl chloride In chloroform at 20℃; for 6h; ketalization;91%
With sulfuric acid at 20℃;65%
With Dess-Martin periodane; toluene-4-sulfonic acid at 20℃; for 20h; Inert atmosphere;63%
58-56-0

pyridoxal hydrochloride

108-94-1

cyclohexanone

4632-05-7

3,4'-O-cyclohexylidenepyridoxine

Conditions
ConditionsYield
With thionyl chloride In chloroform at 20℃; ketalization;90%
With sulfuric acid
Acidic conditions;
58-56-0

pyridoxal hydrochloride

67-64-1

acetone

948-00-5

1,5-dihydro-3,3,8-trimethyl<1,3>dioxepino<5,6-y>pyridin-9-ol

Conditions
ConditionsYield
With thionyl chloride In chloroform at 0 - 20℃; for 7h; ketalization;90%
With hydrogenchloride at 3 - 20℃;87%
(i) HCl, (ii) aq. K2CO3; Multistep reaction;
58-56-0

pyridoxal hydrochloride

67-64-1

acetone

111422-99-2

chlorhydrate d'hydroxy-8 trimethyl-2,2,7 pyrido-<4,5-e>dioxa 1,3-cycloheptane

Conditions
ConditionsYield
With hydrogenchloride at 0℃; for 1h;88%
693-54-9

Decan-2-one

58-56-0

pyridoxal hydrochloride

5-(hydroxymethyl)-2,8-dimethyl-2-octyl-4H-[1,3]dioxino[4,5-c]pyridine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 17h; Reflux; Dean-Stark;87%
58-56-0

pyridoxal hydrochloride

613-94-5

benzoic acid hydrazide

N'-{(3-hydroxyl-5-(hydroxymethyl)-2-methylpyridin-4-yl)methylene}benzohydrazide hydrochloride

Conditions
ConditionsYield
Stage #1: pyridoxal hydrochloride With manganese(IV) oxide; sulfuric acid In water at 60 - 70℃;
Stage #2: benzoic acid hydrazide In water for 0.166667h; Heating;
86%
40615-36-9

4,4'-dimethoxytrityl chloride

58-56-0

pyridoxal hydrochloride

C50H47NO7

Conditions
ConditionsYield
In pyridine; dichloromethane at 20℃; Inert atmosphere;85%
58-56-0

pyridoxal hydrochloride

58479-61-1

tert-butylchlorodiphenylsilane

C40H47NO3Si2

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃;83%
With triethylamine In tetrahydrofuran for 1.5h; Cooling with ice;67%
58-56-0

pyridoxal hydrochloride

100-39-0

benzyl bromide

7442-21-9

[5-(benzyloxy)-4-(hydroxymethyl)-6-methylpyridin-3-yl]methanol

Conditions
ConditionsYield
Stage #1: pyridoxal hydrochloride With potassium carbonate In acetonitrile at 90℃; for 1h;
Stage #2: benzyl bromide In acetonitrile for 3h; Reflux;
83%
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  • Pyridoxine hydrochloride

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    58-56-0

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    58-56-0

    MSDS/COA Download

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    QuickDetails CASNo.:58-56-0 OtherNames:Pyridoxinehydrochloride MF:C8H11NO3 EINECSNo.:NA …Appearance:WHITE FINE POWDER Storage:preserve in tightly sealed,light and oxygen resistant containe

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    58-56-0

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    Vitamin B6 Commodity Name:Vitamin B6 Other Name:Pyridoxine hydrochloride CAS No:58-56-0 M.F.:C8H11NO3.HCl M.W.:205.64 Properties:White or alomost white,crystalline powder,freely soluble in water,slightly soluble in Alcohol,insoluble in

    Founded in 2008, East Chemsources Limited is a professional manufacturer of supplier in food and beverage, pharmaceuticals, cosmetics and other industries. pharmaceutical field in

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    58-56-0

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    vitamin b6/ vitamin b6 powder /GMP approve Vitamin B6 Pyridoxine Hydrochloride,CAS:58-56-0 Introduction: Vitamin B6 is a water-soluble vitamin and is part of the vitamin B complex group. Several forms of the vitamin are known, but py

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    58-56-0

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    Vitamin B6 Pyridoxine hydrochloride Quick details Chemical Name: Vitamin B6 Pyridoxine hydrochloride CAS No.:58-56-0 Molecular Formula:C8H12ClNO3 Molecular weight: 205.64 Appearance: white powder

    Shaanxi Mingqi Chemical Co., Ltd is committed to the development of import and export trade in the production, operation and plant extracts of pharmaceutical raw materials and inte

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    58-56-0

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    Address:Zhengzhou International Trade New Territory,Jinshui District,Zhengzhou ,China

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    1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:A white or almost white crystalline powder Storage:Store in

    Hubei Xinrunde Chemical Co., Ltd. dedicated to the development, production and marketing of chemicals which is specialized in Organic compounds; Active Pharmaceutical Ingredient(s)

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    Business Type:Other

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    Address:No.43, Xinandu Industrial Park, East and West Lake District, Wuhan, Hubei, China

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    58-56-0

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    58-56-0

    MSDS/COA Download

    BLOOM TECH Advanced API/Technology support Pyridoxine (hydrochloride) CAS 58-56-0

    Min.Order: 1 Gram

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    Inquiry guide 1.Please send the quantity(Weight) to us, we will arrange our sales to provide the one-for-one service for you. 2.Then we will provide the professional quotation list for you, it will be including all the factors in who

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    Business Type:Lab/Research institutions

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    58-56-0

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    Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&

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    Business Type:Lab/Research institutions

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    Address:11F, Building A1, No.288 North Zhongshan Road, Gulou District, Nanjing,210003, P.R.China.

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    HUBEI AOKS BIO-TECH CO.,LTD is located in Hubei province of China.We specialized in Active pharmaceutical ingredient,pharmaceutical intermediates,veterinary drug intermediates and

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    58-56-0

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    Business Type:Lab/Research institutions

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    58-56-0

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    Welcome to Hebei Bosang International Trade Co.,Ltd. Hebei Bosang International Trade Co.,Ltd. specializes in exporting high quality Pharmaceutical intermediates,Pharmaceutical

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    58-56-0

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    58-56-0

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    58-56-0

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    CAS RN.: 58-56-0 EINECS: 200-386-2 Molecular Wei

    Wuhan Fortuna Chemical Co., Ltd, located in the predominant Wu Han City where is a traffic hinge of China, is a big integrative chemical enterprise being engaged in producing and

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    Business Type:Trading Company

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    Address:A2705,Dong Yi Shi Qu,129# XinHua Road,WuHan,China

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    58-56-0

    MSDS/COA Download

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    We, Jilin Tely Imp & Exp Co., Ltd. mainly supply and export products including: pharmaceutical raw materials,Chemical reagents, Food additives, pharmaceutical and pesticide interme

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    Business Type:Trading Company

    Tel:+86-0431-81915458

    Address:Room 302, 47 Changping Street, Chaoyang District, Changchun, Jilin Province,China

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    Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

    Shandong Hanjiang Chemical Co., Ltd. is located in Qilu Petrochemical Industrial Park, Zibo City, Shandong Province, involving pesticide, medicine, chemical industry, coating, dy

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    Tel:18369939125

    Address:95A, Xingyuan East Road, Zhangdian District

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    58-56-0

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    CUSTOMIZED LAB Chemtn Biological Technology Limited is one of the leading RC chemicals producer in china,we have advanced equipment and high technology,

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    Address:LB BLDG,Qiaoxi district,Shijiazhuang,china

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    58-56-0

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    1.High quality and competetive price 1)for prulifloxacin exported we can offer coa certificate and official invoice. 2)we are manufacturer with own lab and factory, can provide high quality products with factory price. 3)products purity is tes

    Wuhan New-Rise biochem Co.,Ltd. is a leading provider and manufacturer of pharmaceutical and chemical products. We are dedicated in providing a wide variety of quality API, pharm

  •  Wuhan New-Rise Biochem Co,. Ltd

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Chemistry

 
IUPAC Name: 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride
Molecular Formula: C8H12ClNO3
Molecular Weight: 205.64 g/mol
SMILES: c1(c(cnc(c1O)C)CO)CO.Cl
InChI: InChI=1/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H
EINECS: 200-386-2
Classification Code: Drug / Therapeutic Agent; Human Data; Mutation data; Reproductive Effect; Vitamin [enzyme co-factor] 
Product Categories: Biochemistry; Pyridinium Compounds; Vitamins; Nutritional Supplements; Vitamins and derivatives; Aromatics; Heterocycles; Vitamin Ingredients
Flash Point: 251.3 °C 
Enthalpy of Vaporization: 79.91 kJ/mol 
Boiling Point: 491.9 °C at 760 mmHg 
Melting Point: 214-215 °C(lit.)
storage temperature: 2-8 °C
solubility: H2O: 0.1 g/mL at 20 °C, clear, colorless
Sensitive: Light Sensitive
Stability: Stable. Protect from air and light.
Vapour Pressure of Pyridoxine hydrochloride (CAS NO.58-56-0): 1.71E-10 mmHg at 25 °C

Uses

 Pyridoxine hydrochloride (CAS NO.58-56-0)  is widely used in pharmaceutical ,food and feed additives and also could be used in the cosmetics .

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 intramuscular 500mg/kg (500mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
cat LD50 intravenous 560mg/kg (560mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
cat LD50 oral 1gm/kg (1000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
dog LD50 oral > 500mg/kg (500mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
mouse LD50 intravenous 660mg/kg (660mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
mouse LD50 oral 5500mg/kg (5500mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
mouse LD50 subcutaneous 2450mg/kg (2450mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
pigeon LD50 intravenous 145mg/kg (145mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
rabbit LD50 intravenous 464mg/kg (464mg/kg) PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
rat LD50 intravenous 530mg/kg (530mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
rat LD50 oral 4gm/kg (4000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.
rat LD50 subcutaneous 3gm/kg (3000mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: EXCITEMENT
Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 922, 1961.

Consensus Reports

Reported in EPA TSCA Inventory.

Safety Profile

Hazard Codes: IrritantXi
Risk Statements: 36/37/38 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-37/39 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39: Wear suitable gloves and eye/face protection.
WGK Germany: 2
RTECS of Pyridoxine hydrochloride (CAS NO.58-56-0): UV1350000

Specification

 Pyridoxine hydrochloride (CAS NO.58-56-0), its Synonyms are 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride ; 5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride ; Vitamin B6 hydrochloride ; 2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine hydrochloride ; 3-Hydroxy-4,5-dihydroxymethyl-2-methylpyridine hydrochloride ; 3-Hydroxy-4,5-dimethylol-alpha-picoline hydrochloride ; 4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride ; Aderomine hydrochloride ; 3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride (1:1) . It is crystalline.

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