Journal of Organic Chemistry p. 7153 - 7160 (1995)
Update date:2022-08-03
Topics:
Pearson, Anthony J.
Lee, Kieseung
A convergent synthetic approach to the cyclic peptide 4, which is a model for the B/C/F ring system of ristocetin B, is described.A key reaction is the coupling of the phenolic dipeptide 5, constructed from arylglycine subunits, with the chlorophenylalanine-RuCp cationic complex 6, followed by demetalation of the product to give the diaryl ether 7, without epimerization at any of the amino acid residues.Deprotection of 7 followed by cycloamidation affords the target molecule 4, produced as a mixture of atropdiastereomers which were separated and characterized by NMR spectroscopy.
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Doi:10.1016/0040-4039(95)01324-B
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