Tetrahedron Letters p. 2299 - 2302 (1993)
Update date:2022-08-03
Topics:
Koert, Ulrich
Stein, Matthias
Harms, Klaus
Enantiomerically pure THF-podands 1 were synthesized along a linear route starting from lactone 3. A high degree of stereochemical control was achieved by chelation controlled addition of the functionalized Grignard reagent 7 to α-alkoxy-aldehydes of type 6.
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