Tetrahedron p. 6085 - 6116 (1996)
Update date:2022-08-05
Topics:
Clive, Derrick L. J.
Kong, Xianglong
Paul, Christine Chua
The fredericamycin A analogues 5 and 23 were synthesized. A key step is the process of radical spirocyclization, and the diastereoselectivity of this reaction was studied with model compounds. In vitro tests showed that 23 was active against certain cell lines of colon and prostate cancer, while compound 5 was essentially inactive.
View MoreContact:+86-25-83719363
Address:106-7 Chunnan Rd, Chunxi Town, Gaochun, Nanjing, China
KA-SHING Business Trade Macau Co., Ltd.
Contact:00853-28430045
Address:23rd Floor, Block 3 La Cite, Areia Preta, Macao
Shijiazhuang Sdyano Fine Chemical Co., Ltd
Contact:+86-311-89830448
Address:NO.48 Ta Nan Road,Yuhua District,Shijiazhuang,Hebei,China
Shanggao Ruiya Fine Chemicals Co., Ltd
Contact:+86-795-2592103
Address:Xingguang Nanlu,Shanggao County Industry Park
Goldwills Pharmaceuticals Co., Ltd.
Contact:0916-2237889 13991621155
Address:North Suburb of Hanzhong city, Shaanxi Province
Doi:10.1021/ja953872n
(1996)Doi:10.1002/jhet.5570330238
(1996)Doi:10.1021/ic50010a008
(1963)Doi:10.1021/jo960347d
(1996)Doi:10.1016/0277-5387(95)00503-X
(1996)Doi:10.1016/0040-4039(96)00587-4
(1996)