Enantiomerically pure cyclopropanoid nucleoside analogues: Synthesis and analysis

Article abstract of DOI:10.1016/0040-4020(96)00272-4

Enantiomerically pure cyclopropanoid nucleoside analogues were synthesized by a chemo-enzymatic approach starting from racemic dialkyl 1,2-cyclopropane dicarboxylates. Their enantiomeric purity can be easily verified by HPLC analysis using Chiralcel OD or Chiralcel OD-R columns.