A new catalyst for a Pd catalyzed Alder ene reaction. A total synthesis of (+)-cassiol

Article abstract of DOI:10.1021/ja960642f

The scope of the palladium catalyzed cycloisomerization of enynes in an Alder ene type fashion that led to a new catalytic system was explored in the context of a synthetic strategy to the antiulcerogenic agent (+)-cassiol. In a model study, the effect of