European Journal of Medicinal Chemistry p. 112 - 125 (2019)
Update date:2022-08-03
Topics:
Ma, Xiaodong
Wei, Jun
Wang, Chang
Gu, Dongyan
Hu, Yongzhou
Sheng, Rong
A series of 24 benzothiadiazine derivatives with structural novelty were designed, synthesized and biologically evaluated as PI3Kδ-selective inhibitors. As a consequence of the structure-activity relationship (SAR) study, compounds 63 and 71 were identifi
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