2-Bromo-1-phenylethylidenemalononitrile in the synthesis of thieno[3,2-b]pyridines and thiazolo[4,5-b]pyridines

Article abstract of DOI:10.1007/BF01169260

A novel regioselective synthesis of thieno[3,2-b]pyridines and thiazolo[4,5-b]pyridines from 2-bromo-1-phenylethylidenemalononitrile is proposed. In the case of the thiazolo[4,5-b]pyridines, the intermediate 5-(2,2-dicyano-1-phenylvinyl)thiazoles were separated. Formation of the thiazolo[4,5-b]pyridines was confirmed by x-ray analysis. 1996 Plenum Publishing Corporation.