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Erythritol TOP1 supplier
Cas No: 149-32-6
No Data 100 Gram 100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
Erythritol price/cas 149-32-6
Cas No: 149-32-6
USD $ 2600.0-2600.0 / Metric Ton 1 Metric Ton 6000 Metric Ton/Month Wuxi TAA Chemical Industry Co.,LTD. Contact Supplier
Good supplier of Erythritol / cas:149-32-6
Cas No: 149-32-6
USD $ 2750.0-2750.0 / Kilogram 25 Kilogram 5000 Metric Ton/Month Hefei TNJ chemical industry co.,ltd Contact Supplier
Cas No: 149-32-6
USD $ 2400.0-2500.0 / Metric Ton 1 Metric Ton 100 Metric Ton/Day EAST CHEMSOURCES LIMITED Contact Supplier
Cas No: 149-32-6
No Data 1 Kilogram Metric Ton/Day HANGZHOU CLAKE BIOTECH CO.,LTD Contact Supplier
Natural Sweetener Erythritol CAS 149-32-6
Cas No: 149-32-6
No Data 1 Kilogram 1000 Kilogram/Month Binbo Biological Co., Ltd Contact Supplier
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USD $ 5.0-30.0 / Kilogram 1 Kilogram 5000 Metric Ton/Year Jinan Finer Chemical Co., Ltd Contact Supplier
Food grade organic erythritol 100 mesh cheap price
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No Data 1 Kilogram 10000 Kilogram/Day Baoding Faithful Industry Co., Ltd. Contact Supplier
cas 149-32-6 Natural sweeteners free sample ready stock from Factory 99.8% Erythritol
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No Data 1 Kilogram 1 Metric Ton/Day Hangzhou Fonlynn Health Technology Co., Ltd. Contact Supplier
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USD $ 1.0-1.0 / Metric Ton 1 Metric Ton 100 Metric Ton/Day Bluecrystal chem-union Contact Supplier

149-32-6 Usage

Chemical Properties

Different sources of media describe the Chemical Properties of 149-32-6 differently. You can refer to the following data:
1. white crystals or powder
2. Erythritol (meso-erythritol, meso-1,2,3,4-Tetrahydroxybutan) has been known for a long time. Its potential use as a bulk sweetener was, however, recognized rather late. Erythritol is a natural constituent of several foods and beverages in levels sometimes exceeding 1 g/kg. Its solubility in water is approximately 370 g/L at room temperature and increases with increasing temperature. Erythritol melts at 121 C and is stable up to more than 160 C and in a pH range from 2 to 10. Depending on the concentration used, erythritol is approximately 60 % as sweet as sucrose. It is noncariogenic and not metabolized in the human body which means that it is more or less calorie-free. In the European Union, erythritol is approved as E 968 for a large number of food applications. It is GRAS in the United States and also approved in many other countries.
3. Erythritol is a sugar alcohol (polyol) that occurs as a white or almost white powder or granular or crystalline substance. It is pleasant tasting with a mild sweetness approximately 60–70% that of sucrose. It also has a high negative heat of solution that provides a strong cooling effect.


The sweetness of erythritol is low, the sweetness of erythritol is only 60%-70% of sucrose, the entrance has a cool taste, the taste is pure, and there is no post-bitterness. It can be used in combination with high-intensity sweeteners to inhibit its Undesirable flavors of high-intensity sweeteners. Erythritol has high stability, is very stable to acid and heat, and has high acid and alkali resistance. It will not decompose and change at temperatures below 200 °C, and will not undergo Maillard reaction to cause discoloration. The heat of dissolution of erythritol is high: erythritol has an endothermic effect when dissolved in water, and the heat of dissolution is only 97.4kJ/kg, which is higher than the endothermic degree of glucose and sorbitol, and has a cooling feeling when eating. The solubility of erythritol at 25 °C is 37% (W/W). With the increase of temperature, the solubility of erythritol increases, and it is easy to crystallize and separate out crystals. Erythritol is very easy to crystallize, but it will not absorb moisture in a 90% humidity environment. It is easy to be crushed to obtain a powdery product, which can be used on the surface of food to prevent food from absorbing moisture and deteriorating.


Different sources of media describe the Uses of 149-32-6 differently. You can refer to the following data:
1. Erythritol is a sweetener (polyol) manufactured by fermentation of glucose, the glucose-rich substrate being obtained by the enzymatic hydrolysis of starch. it is 60–70% as sweet as sugar, has excellent heat and acid stability, a high digestive tolerance, and a caloric value of 0.2 kcal/g. it is the only polyol produced by fermentation. it can be used as a sugar replacement in confectioneries, beverages, and desserts.
2. non-cariogenic, low-calorie (0.4 kcal/g) sweetener
3. Non-nutritive sweetener in beverages.


ChEBI: The meso-diastereomer of butane-1,2,3,4-tetrol.

Production Methods

Erythritol is a starch-derived product. The starch is enzymatically hydrolyzed into glucose which is turned into erythritol via a fermentation process, using osmophilic yeasts or fungi (e.g. Moniliella pollinis, or Trichosporonoides megachiliensis).

Biotechnological Production

The synthesis of erythritol is rather difficult. One of the possibilities is the catalytic reduction of tartaric acid with Raney nickel, which does, however, also produce threitol, a diastereomere of erythritol that requires separation of both. Threitol may be isomerized which increases the yields of erythritol. Another chemical synthesis starts from butane-2-diol-1.4 which is reacted with chlorine in aqueous alkali to yield erythritol-2-chlorohydrin and can be hydrolyzed with sodium carbonate solution. Synthesis from dialdehyde starch in the presence of a nickel catalyst at high temperatures is also possible. Owing to the special physiological properties of erythritol, commercial interest increased with the discovery of an increasing number of microorganisms able to produce this substance. Today, the commercial production of erythritol is apparently only based on fermentation. Erythrytitol fermentations mostly use osmophilic yeasts. Based on regulatory submissions for commercial production, T. megachiliensis, M. pollinis, and Y. lipolytica are used. It is also claimed that P. tsukubaensis and Aureobasidium sp. are used for commercial production. Erythritol-producing microorganisms often produce other polyols such as ribitol. Nevertheless, some strains had a rather high yield of erythritol. A two-step fermentation of C. magnoliae on 400 g/L glucose resulted in a 41 % conversion rate and a productivity of 2.8 g/Lh. M. pollinis cultivated on glucose and several nitrogen sources yielded erythritol concentrations up to 175 g/L with a conversion rate of 43 %. Oxygen limitation resulted in ethanol formation, and nitrogen limitation in strong foaming. A mutant gave even better yields. Aerobically on glucose cultured P. tsukubaensis KN 75 produced 245 g/L of erythritol with an especially high yield of 61 %. The productivity was 2.86 g/Lh. Scale-up from 7-L laboratory fermenter to 50,000-L industrial scale resulted in productivities similar to the laboratory value.

General Description

meso-Erythritol, belonging to the class of sugar alcohols, is identified in a variety of food products, fruits, vegetables, beverages and dietary supplements. It is known as a low glycemic food additive and plays an important role as a sweetener for diabetic patients, since it does not have glycemic or insulinemic effect due to its ability to not get metabolized but get absorbed in the small intestine. It is also reportedly used as a sugar substitute in toothpaste, chewing gums, confectionery food products, etc.

Flammability and Explosibility


Pharmaceutical Applications

Erythritol is a naturally occurring noncariogenic excipient used in a variety of pharmaceutical preparations, including in solid dosage forms as a tablet filler, and in coatings. It has also been investigated for use in dry powder inhalers.It is also used in sugar-free lozenges,and medicated chewing gum.Erythritol can also be used as a diluent in wet granulation in combination with moisture-sensitive drugs. In buccal applications, such as medicated chewing gums, it is used because of its high negative heat of solution which provides a strong cooling effect. Erythritol is also used as a noncaloric sweetener in syrups; it is used to provide sensorial profile-modifying properties with intense sweeteners; and it is also used to mask unwanted aftertastes. Erythritol is also used as a noncariogenic sweetener in toothpastes and mouthwash solutions.

Biochem/physiol Actions

Allelic variation of the Tas1r3 gene affects behavioral taste responses to this sugar alcohol, suggesting that it is a T1R3 receptor ligand.


Erythritol is used in oral pharmaceutical formulations, confectionery, and food products. It is generally regarded as a nontoxic, nonallergenic, and nonirritant material. However, there has been a case report of urticaria caused by erythritol. The low molecular weight of erythritol allows more than 90% of the ingested molecules to be rapidly absorbed from the small intestine; it is not metabolized and is excreted unchanged in the urine. Erythritol has a low caloric value (0.8 kJ/g). The WHO has set an acceptable daily intake of ‘not specified’ for erythritol. Erythritol is noncariogenic; preliminary studies suggest that it may inhibit the formation of dental plaque. In general, erythritol is well-tolerated; furthermore, excessive consumption does not cause laxative effects. There is no significant increase in the blood glucose level after oral intake, and glycemic response is very low, making erythritol suitable for diabetics. LD50 (mouse, IP): 8–9 g/kg LD50 (rat, IV): 6.6 g/kg LD50 (rat, oral): >13 g/kg


Erythritol has very good thermal and chemical stability. It is nonhygroscopic, and at 25°C does not significantly absorb additional water up to a relative humidity (RH) of more than 80%. Erythritol resists decomposition both in acidic and alkaline media and remains stable for prolonged periods at pH 2–10.(10) When stored for up to 4 years in ambient conditions (20°C, 50% RH) erythritol has been shown to be stable.

Purification Methods

meso-Erythritol crystallises from distilled water or absolute EtOH and is dried at 60o in a vacuum oven. It sublimes at 110o in a high vacuum. It is optically inactive. [Jeans & Hudson J Org Chem 20 1565 1955, IR: Kuhn Anal Chem 22 276 1950, Beilstein 1 IV 2807.]


Erythritol is incompatible with strong oxidizing agents and strong bases.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe.

Check Digit Verification of cas no

The CAS Registry Mumber 149-32-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 9 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 149-32:
56 % 10 = 6
So 149-32-6 is a valid CAS Registry Number.

149-32-6 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Alfa Aesar (A15813)  meso-Erythritol, 99%    149-32-6 25g 368.0CNY Detail
Alfa Aesar (A15813)  meso-Erythritol, 99%    149-32-6 100g 1095.0CNY Detail
Alfa Aesar (A15813)  meso-Erythritol, 99%    149-32-6 500g 4655.0CNY Detail
Sigma-Aldrich (73132)  meso-Erythritol  analytical standard 149-32-6 73132-100MG 616.59CNY Detail
Sigma-Aldrich (PHR1479)  Erythritol  pharmaceutical secondary standard; traceable to USP and PhEur 149-32-6 PHR1479-1G 813.27CNY Detail
Sigma-Aldrich (Y0000177)  Erythritol  European Pharmacopoeia (EP) Reference Standard 149-32-6 Y0000177 1,880.19CNY Detail
USP (1241903)  Erythritol  United States Pharmacopeia (USP) Reference Standard 149-32-6 1241903-200MG 4,326.66CNY Detail



According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017


1.1 GHS Product identifier

Product name butane-1,2,3,4-tetrol

1.2 Other means of identification

Product number -
Other names 1,2,3,4-Butanetetrol, (R*,S*)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Food additives
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:149-32-6 SDS

149-32-6Related news

Enthalpies of dilution of aqueous solutions of n-butanol, butanediols, 1,2,4-butanetriol, and 1,2,3,4-Butanetetrol (cas 149-32-6) at 298.15K09/28/2019

Enthalpies of dilution of aqueous solutions of 1-butanol, butanediols, 1,2,4-butanetriol and 1,2,3,4-butanetetrol (erythritol), were measured at 298.15K, using a LKB flow microcalorimeter. Experimental data were treated according to the McMillan–Mayer theory, to obtain the enthalpic interaction...detailed

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