Tetrahedron Asymmetry p. 1929 - 1942 (1996)
Update date:2022-08-05
Topics:
Occhiato, Ernesto G.
Scarpi, Dina
Menchi, Gloria
Guarna, Antonio
The enantioselective reduction of γ-nitroketones 1-4 and γ-nitrodiketones 5-6 by the chiral reducing agent (+)- or (-)-diisopinocampheylchloroborane (DIP-Cl(TM)) afforded respectively nitroalcohols 7-9 with e.e's ranging from 33 to 86% and nitrodiols 11-12 with complete diastereoselectivity and e.e. > 95%. Nitrodiols (1S,7S)-11 and (1S,7S)-12 were then used as chiral precursors for the synthesis of the enantiopure 2,7-diphenyl- and 2,7-di-(2'-methoxyphenyl)-2,6-dioxaspiro[4.4]nonanes, 21 and 22, as EE/ZZ mixtures.
View MoreKaymossy BioChem Tech Co., Ltd
website:http://www.kaimosi.com
Contact:0571-87191913/0571-87199097
Address:Room 215, Building 3rd, No.288 Ningxia Road, Qingdao city, China
Contact:+86-021-58123769
Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
Anhui Dexinjia Biopharm Co., Ltd
Contact:+86-531-82375818
Address:9 Hexie Road, kaifaqu, Taihe
Shanghai Sunway Pharmaceutical Technology Co.,Ltd.
Contact:+86-21-5161 3915
Address:Shanghai YangPu
Nanjing Zelang Medical Technology Co. Ltd
Contact:86-25-83063290/13770714480
Address:Ganjiabian 108# 01 Unit,701-702 room,Yao Hua Street,Qixia District,Nanjing,Jiangsu,China
Doi:10.1080/15257779508012536
(1995)Doi:10.1055/s-1974-23249
(1974)Doi:10.1021/jo00838a048
(1969)Doi:10.1021/ja963002l
(1996)Doi:10.1016/S0008-6215(01)00231-2
(2001)Doi:10.1002/hlca.19960790724
(1996)