Synthesis of C-branched spermine tethered oligo-DNA and the thermal stability of the duplexes and triplexes

Article abstract of DOI:10.1016/0040-4020(96)00731-4

The first synthesis of the new C-branched spermine derivative 17, as well as its ability to stabilise DNA duplexes and triplexes, are reported. The C-branched spermine block 17 was converted into the corresponding O-(2-cyanoethyl)-(N,N-diisopropyl)phospho