Tetrahedron p. 15117 - 15126 (1996)
Update date:2022-07-30
Topics:
Langlois, Nicole
Dahuron, Nathalie
Wang, Hai-Shan
Enantioselective synthesis of (R)-4-amino-3-phenylbutyric acid and (R)-baclofen has been achieved through a diastereoselective conjugate addition of cyanide to enantiomerically pure 2-(2-arylethenyl)oxazolines, followed by chemoselective reduction into cyclic amidines.
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